Failure to Fund, Part One
The first in a meditation on the National Institutes of Health's failure to fund ME research for three decades. How they managed it and who made it work.
David Bell, Part Two: Low Blood Volume in Myalgic Encephalomeylitis--Shocking
Is the flashy technology of the day driving the direction of ME research or are the time-honored values of clinical observation and logic driving it? A look at low blood volume in ME, offered by former Lyndonville, NY pediatrician David Bell. The latter is concerned that some of the most basic organic findings in the disease, in this case low blood volume, are being left unexplored while advanced techniques of the day are focusing on microscopic abnormalities that may or may not lead to a central understanding of ME. A lot of ME sufferers have so little blood circulating in their vascular systems they are in a state of "persistent shock," Bell says. The lack of an adequate blood supply leads not only to orthostatic intolerance, a near-universal autonomic symptom in patients, but could explain many of the most life-threatening and debilitating aspects of the disease, including stroke, cardiac disorders, and even the mechanisms of death in ME. Bell and I discuss the manifestations and implications of low blood volume in ME and wonder--shouldn't investigators be trying to understand this shocking and possibly universal abnormality?